Recently, researchers from Massachusetts General Hospital and Harvard Medical School found that blue light can selectively eradicate Pseudomonas aeruginosa infections in the skin and soft tissues without causing damage to the outer skin. Related papers were published online in the journal "Antibacterial Agents and Chemotherapy" of the American Society of Microbiology.
Michael Hamblin, who is in charge of the study, said that blue light is a potentially non-toxic, non-antibiotic therapy for treating skin and soft tissue infections, especially for infections caused by antibiotic-resistant bacteria.
In this study, the researchers conducted experiments on animal models infected with Pseudomonas aeruginosa, and the results showed that all animals treated with blue light survived, while in the control group without blue light treatment, 82% ( 9 out of 11 animals died.
Many germs have extremely strong replication ability. In response to antibiotics, they will rapidly mutate and occupy a dominant position in the entire microbial population. A recent example of a super bacteria called DM-1 is an example. This kind of bacteria is extremely resistant. At present, in addition to the three antibiotics tigecycline, colistin and vancomycin, other antibiotics It has no killing effect on these bacteria. The outbreak of antibiotic resistance is making the treatment of such infections more complicated, and many doctors even believe that some infections will become incurable in the near future.
In addition to endangering public health, the increase in antibiotic resistance has further increased medical costs. Treatment of soft tissue and skin infections often requires the use of more expensive drugs, which may result in longer hospital stays for infected patients. Skin and soft tissue infections are the second most common bacterial infections encountered in clinical practice. In the United States, patients hospitalized due to skin and soft tissue infections account for about 10% of the total number of patients. Together with about 142,000 outpatients, the annual medical expenses are US $ 24 billion, which is an average of US $ 76 per American.
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