With the global economy entering a new normal, people in a harmonious society began to pay more attention to personal health care, health care can not be separated from the help of various health care drugs. Then the authenticity of the drug has become a very important part of it. In addition to quantitative chemical analysis instruments, polarized light microscopy is undoubtedly one of the most authoritative standard procedures.
1 Application in mineral Chinese medicine
Most of the mineral-based Chinese medicines are crystalline minerals, such as gypsum, quartz, mica stone, cold water stone, etc., strong and multi-colored interference ribbons appear in the dark field, which is very obvious and obvious. Using the stage with a disc, the double color and extinction of various mineral drugs can be observed, and the refractive properties, dissociation angle and extinction angle of minerals specific to many mineral drugs can be accurately measured. . Some experts used a polarizing microscope to observe the surface of the pearl as one of the main evaluation criteria for pearls. Therefore, polarized light microscopy is an important technical tool for identifying mineral medicines such as Tibetan medicine.
Dimethyl ammonia crystal
2 application in animal Chinese medicine
The bones and teeth of the animal can not be seen carefully under a normal microscope, but under the polarizer, there is a strong contrast of color and stripes. Polarization can also distinguish between normal cells and tumor cells, because normal cells are often left-handed for polarized light, while tumor cells are mostly dextrorotatory; some animals' striated muscles and hair can also be examined with polarizers. Therefore, many animal medicinal materials such as leopard bone, ivory, sea dragon, seahorse, turtle shell, armor, snake, etc., even include many animal horns, stones, secretions, such as antlers, antelope horns, bezoar, Ma Bao, monkey dates , pearls, musk, bird's nest, etc. can be considered (such as traditional cream)
Check with a polarizing microscope. It has been reported that the content of adulterated substances in musk medicinal materials can be measured by a polarizing microscope.
Horse uric acid crystal
3 application in plant medicinal materials
Many plant medicinal materials have stable and specific polarization phenomena in their tissues, cells and inclusions. The application of polarizer observation can quickly and accurately find the identification features and eliminate interference. Some experts have used polarizers to find 8 kinds of starch granules such as astragalus, 12 kinds of calcium oxalate crystals such as ginseng, 7 kinds of stone cells such as peach kernel, 5 kinds of catheters such as hawthorn, and 8 kinds of fibers such as Shichangpu, which have stable and specific polarization characteristics. And mainly use polarizer to identify the Zhibao Sanhui pill containing 34 kinds of herbs through the respective polarizing characteristics of the medicinal materials. We found that the plant cell walls, ducts, fibers, and resin walls of the Araliaceae plants, such as ginseng, panax notoginseng, and American ginseng, have strong polarizing phenomena. This characteristic is used to test the Sanqi tablets, Yangshen pills, etc. The proprietary Chinese medicines used in medicine have played a fast and accurate role. (such as Chinese patent medicine)
3.1 starch granules
All plant starch granules have a polarizing phenomenon. Under the polarizer, in the dark background, the starch granules appear brightly spherical with two criss-crossed dark stripes, and the intersection is the umbilical point of the starch granules. (various tablets, capsules
Asparagine crystal
For more than 160 years, Leica has been developing and manufacturing top-of-the-line polarizing microscopes. The latest DM750P, DM2700P and DM4P are highly recognized by domestic pharmaceutical industry professionals and are the first choice for the identification of polarized properties of pharmaceutical materials!
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